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患者女,26岁,未婚。从1986年10月起接触甲苯、二甲苯7个月,产品为盐酸苯丙醇胺。自1987年5月起试制合成肾上腺皮质激素——六甲基强的松龙醋酸酯,主要接触纯苯,每日接触量约110升,加热至80℃脱水反应,管道因密闭不严,苯蒸气常逸出,且门窗关闭,无防护设施,故苯味较浓,仅患者1人操作。1987年10月,患者出现经量增多,行经期需用卫生纸6包,经期由3天延长至6天,周期无变化。一年后检查血红蛋白90～52g/L,白细胞5.2×10~9/L,月经周期紊乱,21～40余天不等。拟诊缺铁性贫血,口服铁剂3个月,血红蛋白上升至96g/L 时停药。继续参加生产,即将成品粉末烘干、分装,均敞
Female patient, 26 years old, unmarried. From October 1986 from contact with toluene, xylene 7 months, the product is phenylpropanolamine hydrochloride. Since May 1987 trial synthesis of adrenal cortex hormones - hexamethyl prednisolone acetate, the main exposure to benzene, the daily exposure of about 110 liters, heated to 80 ° C dehydration reaction, the pipeline due to airtight, benzene Vapors often escape, and the doors and windows closed, non-protective facilities, it is benzene-rich, only 1 patient operation. October 1987, patients with increased volume, the menstrual period need to use 6 packets of toilet paper, menstrual period from 3 days to 6 days, no change in the cycle. One year after the examination of hemoglobin 90 ~ 52g / L, white blood cells 5.2 × 10 ~ 9 / L, menstrual cycle disorders, ranging from 21 to 40 days. To be diagnosed with iron deficiency anemia, oral iron 3 months, hemoglobin rose to 96g / L withdrawal. Continue to participate in the production, about finished powder drying, packaging, are spacious