The mechanism of the electrochemical reduction of 5-nitrouracil

来源 :Acta Chimica Sinica(English Edition) | 被引量 : 0次 | 上传用户:jlsonger
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The electrochemical reduction of 5-nitrouracil (5NU) has been investigated on Ag-Hgcathode in DMSO by cyclic voltammetry and controlled potential electrolysis,in combination withUV and ESR spectroscopies.The results showed that 5NU proceeds in a four-electron reduction andsimultaneously participates in the reaction as a proton donor.At a more negative potential,the 5NUanion (5NU~-) thus formed is reduced further through a one-electron process to a dianion whoseESR.parameters have been determined as aN=14.6 G,aH=5.2 G and g=2.005.The radicaldecay process might be conjectured through protonization by accepting protons from 5NU,of whichthe rate constant k_1=52 M~(-1)·s~(-1). The electrochemical reduction of 5-nitrouracil (5NU) has been investigated on Ag-Hgcathode in DMSO by cyclic voltammetry and controlled potential electrolysis, in combination with UV and ESR spectroscopies. The results showed that 5NU went in a four-electron reduction and minimized participates in the reaction as a proton donor. At a more negative potential, the 5NUanion (5NU ~ -) thus formed is reduced further through a one-electron process to a dianion whose ESR.parameters have been determined as aN = 14.6 G, aH = 5.2 G and g = 2.005. The radical decision process might be conjectured through protonization by accepting protons from 5NU, of which the constant rate k_1 = 52 M -1 s -1.
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