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目的,研究砷在人体内蓄积排泄情况和皮肤色素改变水砷的关系,综合评价新疆奎屯改水防病的效果。方法:调查研究了由天然井水引起的地方性砷中毒。流行地区居民在改水前后尿砷水平及皮肤色素改变的情况。结果表明:改饮正常水后,居民体内砷呈一慢性排出过程。经改水16年后尿砷均恢复正常,但与正常人群相比仍有差异,改水后男、女尿砷水平及下降水平无性别差异。改水后皮肤病变阳性的检出率低于改水前。结论:改术能解除体内的高砷状态。尿砷含量可反映机体内砷的蓄积,是评价机体砷接触的一个重要指标。
Aims To study the relationship between accumulation and excretion of arsenic in human body and changes of water and arsenic in skin pigmentation, and evaluate the effect of water and disease prevention in Kuitun, Xinjiang. Methods: Investigations were made on endemic arsenic poisoning caused by natural well water. Urine and urinary arsenic levels and skin pigmentation changes in residents of endemic areas before and after water diversion. The results showed that: After drinking normal water, the residents had a chronic excretion of arsenic. Urinary arsenic returned to normal after 16 years of water change, but there was still a difference compared with the normal population. There was no gender difference in urinary arsenic levels and declining levels of male and female urine after changing water. The detection rate of positive skin lesions after water change is lower than before water change. Conclusion: Ameliorating can relieve high arsenic in the body. Urinary arsenic content can reflect the accumulation of arsenic in the body, is an important indicator to evaluate the body’s arsenic exposure.