p16过表达可识别HPV阳性的外阴鳞状细胞癌

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根据与人乳头状病毒(HPV)的关系,外阴鳞状细胞癌可分为两类:HPV相关的基底细胞样癌或疣状癌和非HPV相关的分化性角化型癌。近来提出用p16和p53的免疫组化染色来区分这两类外阴鳞癌。为评价免疫组化在外阴鳞癌分类中的作用、阐明这两类外阴鳞癌的临床病理特征,本课题对92例外阴 According to the relationship with human papillomavirus (HPV), vulvar squamous cell carcinoma can be divided into two categories: HPV-related basaloid carcinoma or verrucous carcinoma and non-HPV associated differentiated keratinized carcinoma. Recently proposed using p16 and p53 immunohistochemical staining to distinguish between these two types of vulvar squamous cell carcinoma. In order to evaluate the role of immunohistochemistry in the classification of vulvar squamous cell carcinoma and to elucidate the clinicopathological features of these two types of vulvar squamous cell carcinoma, 92 cases of genital
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