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瘤型麻风是个系统性疾病,内分泌系统亦会受累。瘤型麻风睾丸受侵害很常见,肾上腺很少见大的变化,但束状带、网状带和髓质静脉周围常见小结节变化,因此,可能产生肾上腺功能不全,引起尿17-酮类固醇排出量减少。瘤型麻风肝损害亦很常见,Shivda等报告40％、Camain等报告90％有特异性改变,它可使尿17-酮类固醇排出量减少。因此,作者对瘤型麻风尿17-酮类固醇与肝损害的关系进行了研究。研究病例共29例,其中男23名,女6名;年龄20～50岁,均已接受抗麻风治疗;病期3～24年;肾功能正常,没有反应;睾丸萎缩者6例(20.6％),男性乳房肿大者3例(10.3％)。
Leprosy is a systemic disease, the endocrine system will be involved. Tumor-type leprosy testicles are inflicted very infrequently, adrenal glands rarely change much, but fascicular, nodal and medullary venous common small nodular changes, therefore, may produce adrenal insufficiency, urinary 17-ketosteroid Emissions reduced. Tumorous leprosy liver damage is also common, Shivda other reports of 40%, Camain and other reports of 90% of the specific changes, it can reduce the urinary 17-keto steroid emissions. Therefore, the authors studied the relationship between tumor-associated leprosy 17-keto steroids and liver damage. A total of 29 cases, including 23 males and 6 females; aged 20 to 50 years old, have received anti-leprosy treatment; period of 3 to 24 years; normal renal function, no response; testicular atrophy in 6 cases (20.6% ), 3 cases of male breast enlargement (10.3%).