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重症肝炎(包括急性、亚急性肝坏死)是在一般黄疸型病毒性肝炎基础上造成大量肝细胞坏死或严重性肝功能损害。临床表现的特点是起病急骤,黄疸进行性加深,肝萎缩,腹水,出血倾向,颅内压增高,严重神志改变,甚至昏迷。在并发呼吸衰竭,肝肾综合征,脑水肿,胃肠道出血,继发感染等合并症时,如不能及时诊治,预后极差,死亡率甚高。重症肝炎发病机制至今尚未明确,目前国内、外的治疗方法繁多,但尚无任何一种肯定有效的疗法。我院1970~1974年共收治20例,其中12例死亡,存活8例中尚有2例发展成为坏死后性肝硬化,故必须引起我们足够的重视,并强调
Severe hepatitis (including acute, subacute hepatic necrosis) is caused by a large number of liver cell necrosis or severe liver damage on the basis of general jaundice-type viral hepatitis. Clinical manifestations are characterized by sudden onset, progressive jaundice, liver atrophy, ascites, bleeding tendency, increased intracranial pressure, severe mental changes, and even coma. In concurrent respiratory failure, hepatorenal syndrome, cerebral edema, gastrointestinal bleeding, secondary infection and other complications, if not timely diagnosis and treatment, poor prognosis, high mortality. The pathogenesis of severe hepatitis has not yet been established. At present, there are many treatments at home and abroad, but there is not any definite and effective treatment. In our hospital from 1970 to 1974, a total of 20 cases were treated, of which 12 died and 8 of 8 survived and survived to develop into post-necrotic cirrhosis, so we must pay enough attention to it and emphasize