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在移植学会纽约会议上,美国明尼苏达医院大学Najarian教授报告,接受胰岛细胞移植的糖尿病患者,其胰岛素需要量减少。胰岛细胞系来自婴儿或成人新鲜尸体的胰腺。10名患者进行胰岛细胞移植。其中包括7例因晚期糖尿病性肾病而曾行同种肾移植者,被移植的肾脏功能正常;行胰岛细胞移植时,患者均正在使用免疫抑制疗法。胰岛细胞的移植方法:腹膜内5例,肌肉内1例,经门静脉者4例;其中门静脉可能是最好的部位,因肝脏接受门静脉和肝动脉两支良好的血供。移植的细胞数量也不同,胰岛组织的量以其总胰岛素含量计算,并以正常成人胰腺的百分率表示,肌肉内移植者为14％,腹膜内为<1％～8％,门静脉为<1％～11％。移植后,3例胰岛素
At the Transplantation Society’s New York conference, Professor Najarian at the University of Minnesota Hospital reported that patients with diabetes who underwent islet cell transplantation had lower insulin requirements. Islet cell lines are from the pancreas of infants or adult fresh cadaver. Ten patients underwent islet cell transplantation. Including 7 patients with advanced renal allografts due to diabetic nephropathy who had normal kidney function was normal; transplant islet cell transplantation, patients are using immunosuppressive therapy. Islet cell transplantation methods: intraperitoneal in 5 cases, intramuscular in 1 case, the portal vein in 4 cases; of which the portal vein may be the best site for the liver to accept the portal vein and hepatic artery two good blood supply. The number of transplanted cells is also different. The amount of islet tissue is calculated from its total insulin content and is expressed as a percentage of normal adult pancreas, with 14% being intramuscularly grafted, <1% -8% intraperitoneally, <1% ~ 11%. After transplantation, 3 cases of insulin