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目前,关于癌症基础遗传学研究的重点是染色体和基因的改变能诱发恶性肿瘤的机制。本文仅就人类染色体研究的基本方法及染色体异常诱发恶性肿瘤的机制加以介绍。人类染色体研究的基本方法研究人类染色体的主要目的之一是期望得到能够和肿瘤细胞相比较的正常人类染色体核型。但由于在标本制作方面遇到的困难阻碍了对其研究的不断进展。直到本世纪五
At present, the research on basic cancer genetics focuses on the mechanisms by which chromosomal and genetic changes can induce malignant tumors. This article only on the basic methods of human chromosome research and chromosomal abnormalities induced malignant tumors are introduced. Basic Methods for Human Chromosome Research One of the primary purposes of studying human chromosomes is to expect to obtain normal human karyotypes that are comparable to tumor cells. However, due to difficulties encountered in specimen preparation, it hindered the progress of its research. Until this century five