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目的:探讨哮喘儿童体质指数(Body mass index,BMI)和肺功能的变化。方法:观察202例儿童,其中哮喘患儿102例,对照组100例,分别计算BMI值,两组肥胖患儿进行血嗜酸性粒细胞及肺功能测定。结果:哮喘组肥胖发病率22.5%,而对照组肥胖发病率8%(P<0.01);哮喘组患儿嗜酸性粒细胞数较对照组明显增高(P<0.05);哮喘组肥胖患儿肺功能(FEV1,FVC,PEF,FEV1/FVC)明显低于对照组(P<0.05)。结论:儿童哮喘与肥胖密切相关。
Objective: To investigate the changes of body mass index (BMI) and pulmonary function in children with asthma. Methods: Totally 202 children, including 102 asthmatic children and 100 control subjects, were enrolled in the study. The BMI was calculated and the blood eosinophils and pulmonary function were measured in two obese children. Results: The incidence of obesity in asthma group was 22.5%, while the incidence of obesity in control group was 8% (P <0.01). The number of eosinophils in asthmatic group was significantly higher than that in control group (P <0.05) Function (FEV1, FVC, PEF, FEV1 / FVC) was significantly lower than that of the control group (P <0.05). Conclusion: Childhood asthma is closely related to obesity.