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目的:探讨抗高血压治疗与老年人认知功能得分的关系。方法:采用多阶段整群抽样,抽取贵阳市60岁以上老年患者3229例进行问卷调查和体格检查,收集其高血压的患病和治疗情况并检测血压,用标准化简易智力量表进行认知功能测定,资料统计分析方法采用u检验和协方差分析。结果:单因素与协方差分析均显示,高血压未治疗组在总体认知功能与各认知功能域得分方面均低于高血压治疗组,尤其在定向力、记忆力、注意力和计算力、语言能力方面表现明显;按治疗时间分组的协方差分析结果显示,在总体认知功能与各认知功能域得分方面,>6年组均高于≤6年组,但2者差异无统计学意义。结论:抗高血压治疗可延缓老年人认知功能下降,尤其表现在定向力、记忆力、注意力和计算力、语言能力领域,可能有助于减少老年痴呆的发生。并未发现长期抗高血压治疗比短期抗高血压治疗更能延缓总体认知功能下降。
Objective: To investigate the relationship between antihypertensive treatment and cognitive function in the elderly. Methods: Using multistage cluster sampling, 3229 senile patients over the age of 60 in Guiyang City were sampled for questionnaire and physical examination. The prevalence and treatment of hypertension were collected and blood pressure was measured. Cognitive function Measurement, data statistical analysis using u test and covariance analysis. Results: Univariate analysis and covariance analysis showed that the hypertension untreated group was lower than the hypertensive group in overall cognitive function and cognitive domain score, especially in the direction of orientation, memory, attention and computational power, Language covariance analysis showed that in the overall cognitive function and each cognitive domain score,> 6-year group were higher than 6 years group, but the difference was not statistically significant significance. Conclusion: Antihypertensive treatment can delay the decline of cognitive function in the elderly, especially in the field of orientation, memory, attention and computational power, language ability and may help reduce the incidence of dementia. Long-term antihypertensive treatment has not been found to delay overall cognitive decline more than short-term antihypertensive treatment.