论文部分内容阅读
本实验研究了交感神经缩血管作用对已狭窄的冠状动脉节段阻力的作用。 方法 在14条麻醉开胸犬,人工通气,维持动脉PO_2于70～80mmHg,pH7.35～7.45。分离冠状动脉左旋支主干,分别测量左旋支流量,左旋支远端冠状动脉压及胸主动脉压,记录心电图。预先冠状动脉内输人心得安1mg,以显露心交感神经的缩血管作用。电刺激左侧星状神经节(LSGs)。在冠状动脉上系缩窄环,造成临界(中度)狭窄及重度狭窄。冠状动脉节段阻力的
This study investigated the effect of sympathetic vasoconstriction on stenosed coronary artery segmental resistance. Methods In 14 anesthetized thoracotomy dogs, artificial ventilation was performed to maintain arterial PO_2 at 70-80 mmHg and pH 7.35-7.45. The left main branch of the coronary artery was isolated and the left tributary flow volume, distal left coronary artery pressure and thoracic aortic pressure were measured and the electrocardiogram was recorded. Prednisolone propranolol 1mg, to reveal the sympathetic vasoconstrictive effect. Electrical stimulation of left stellate ganglion (LSGs). Narrow the ring in the coronary artery, resulting in critical (moderate) stenosis and severe stenosis. Coronary artery segment resistance