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从1972～1977年,作者对598例临床Ⅰ期皮肤黑素瘤患者进行连续观察和前瞻性病情分析,除去削皮法或广面积切除活检的126例(21％),对其余的472例患者(男230,女242;年龄18～91岁)进行活检类型对存活率影响分析。 472例患者中,119例(25％)部分切除活检(IB),353例(75％)全部切除活检(EB)。按肿瘤厚度和活检类型结果将患者分为4个组进行分析,其结果是黑素瘤厚度<0.85mm组,IB组46例没有1例死亡,EB组111例仅1例死亡。肿瘤厚度0.85～1.69mm组,IB组30例全部存活,EB组119例,6例(5％)死于黑素瘤。肿瘤厚度1.70～3.64mm组,IB21组例有7例(33％)死亡,EB组79例有14例(18％)
From 1972 to 1977, the authors performed continuous observations and prospective analysis of 598 patients with stage I cutaneous melanoma. 126 patients (21%) were excluded from peeling or wide-area resection biopsies, and 472 patients were remaining. (Male 230, Female 242; Age 18-91 years) Analyze the effect of biopsy type on survival. Of the 472 patients, 119 (25%) were partially resected biopsies (IB) and 353 (75%) were completely resected biopsies (EB). According to the tumor thickness and biopsy type results, the patients were divided into 4 groups for analysis. The results showed that the thickness of melanoma was less than 0.85mm group. There was no death in 46 patients in group IB, and only 1 case died in 111 patients in group EB. Tumor thickness 0.85 to 1.69 mm group, 30 patients in group IB all survived, 119 patients in EB group, 6 patients (5%) died of melanoma. Tumor thickness 1.70 to 3.64mm group, IB21 group 7 cases (33%) died, and EB group 79 cases (18%)