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肝细胞生长因子(HGF)是一种内皮细胞特异性生长因子,促进内皮细胞的增殖和移行,抑制内皮细胞的凋亡。高血压患者血清HGF水平与血压高低、靶器官损害程度和血压节律异常有关,可能成为反映高血压内皮功能不全的一个新指标。一些药物能降低高血压患者血清HGF水平。
Hepatocyte growth factor (HGF) is an endothelial cell-specific growth factor that promotes endothelial cell proliferation and migration and inhibits endothelial cell apoptosis. Hypertensive patients with serum levels of HGF and blood pressure, target organ damage and abnormal blood pressure rhythm may be a reflection of endothelial dysfunction in a new indicator of hypertension. Some drugs can reduce serum HGF levels in hypertensive patients.