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肝癌(HCC)是当今世界最常见恶性肿瘤之一。其发病与地理位置密切相关。好发于亚州和南非,少见于地中海盆地,西欧和北美最少。HCC 的病因在高流行区与乙型肝炎病毒(HBV)和大结节性肝硬变有关。另外石化产品、合成代谢产物、甾体避孕药、血色素病和α_1-抗胰蛋白酶缺乏亦是重要致病因素,通常合并有肝硬变。不同地理位置以及不同人种 HCC 临床特征表现不同。
Liver cancer (HCC) is one of the most common malignancies in the world today. Its incidence and geographical location are closely related. Occurred in Asia and South Africa, rare in the Mediterranean basin, Western Europe and North America at least. The etiology of HCC is associated with hepatitis B virus (HBV) and large nodular cirrhosis in high endemic areas. In addition, petrochemicals, anabolic products, steroidal contraceptives, hemochromatosis and alpha 1-antitrypsin deficiency are also important risk factors, often associated with cirrhosis. Different geographical locations and different ethnic HCC clinical characteristics of different performance.