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中国传统医学对丸剂有“丸者缓也,缓而治之…”的记载,可见我国古代的医学家早已认识到药剂延缓释放可以获得平稳持久的治疗效果。医学发展到今天,人们已不仅限于中药的丸剂,而把缓慢释药的特点应用到现代医学中的各种药物中,研制成了缓释、控释制剂。近三十年来,由于其独特的作用方式和特点,缓释、控释制剂得到了迅速的发展和应用。 “缓释制剂”,就是延长药物在体内的吸收、分布、代谢和排泄过程,从而达到延长药物作用时间的一类制剂。“控释制剂”在现代医学中还没有明确的定义,
Chinese traditional medicine on the pills have “pills are gentle, gentle treatment of ...” records, we can see ancient Chinese physicians have long recognized the delay in the release of drugs can be stable and lasting therapeutic effect. Nowadays, people have not only confined to traditional Chinese medicine pills, but have applied the characteristics of slow drug release to various medicines in modern medicine. They have been developed into sustained release and controlled release preparations. Nearly three decades, due to its unique mode of action and characteristics, sustained release, controlled release formulations have been rapid development and application. “Sustained-release preparations” is to extend the absorption, distribution, metabolism and excretion of drugs in the body, so as to achieve a class of agents to extend the duration of the drug. “Controlled-release preparations” in the modern medicine has not been clearly defined,