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据科学网2017年4月14日报道,中国农科院哈尔滨兽医所基础免疫研究团队在艾滋病天然免疫研究领域获得了新的发现:通过对丝氨酸整合因子(SERINC)家族5个成员系统性比对,发现SERINC5具有的抗病毒活性最高,还检测到了该分子在人体细胞中表达的5种不同分子亚型;5种亚型中只有Ⅰ亚型能够高效表达;相较于其他亚型,Ⅰ亚型多了一个跨膜区,从而增强了蛋白稳定性并产生抗病毒效力;Ⅰ亚
According to the science net reported on April 14, 2017, the basic immunology research team of Harbin Veterinary Institute of Chinese Academy of Agricultural Sciences has made new discoveries in the field of AIDS natural immune research: By systematically aligning 5 members of the serine integration factor (SERINC) family, , Found that SERINC5 has the highest antiviral activity and also detected five different molecular subtypes of the molecule expressed in human cells; only the I subtypes of the five subtypes were highly expressed; compared to other subtypes, Type a more transmembrane region, thereby enhancing protein stability and produce antiviral efficacy; Ⅰ Asia