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The aluminum shielded room has been an important part of ultra-low-field magnetic resonance imaging (ULF MRI) based on the superconducting quantum interference device (SQUID).The shielded room is effective to attenuate the exteal radio-frequency field and keep the extremely sensitive detector,SQUID,working properly.A high-performance shielded room can increase the signal-to-noise ratio (SNR) and improve image quality.In this study,a circular coil with a diameter of 50 cm and a square coil with a side length of 2.0 m was used to simulate the magnetic fields from the nearby electric apparatuses and the distant environmental noise sources.The shielding effectivenesses (SE) of the shielded room with different thicknesses of aluminum sheets were calculated and simulated.A room using 6-mm-thick aluminum plates with a dimension of 1.5 m× 1.5 m×2.0 m was then constructed.The SE was experimentally measured by using three-axis SQUID magnetometers,with tranisent magnetic field induced in the aluminum plates by the strong pre-polarization pulses.The results of the measured SE agreed with that from the simulation.In addition,the introduction of a 0.5-mm gap caused the obvious reduction of SE indicating the importance of door design.The nuclear magnetic resonance (NMR) signals of water at 5.9 kHz were measured in free space and in a shielded room,and the SNR was improved from 3 to 15.The simulation and experimental results will help us design an aluminum shielded room which satisfies the requirements for future ULF human brain imaging.Finally,the cancellation technique of the transient eddy current was tried,the simulation of the cancellation technique will lead us to finding an appropriate way to suppress the eddy current fields.