Oxidative stress and antioxidants in hepatic pathogenesis

• 作 者: Hye-Lin Ha Hye-Jun Shin Mark A
• 机 构: DiseaseModelResearchLaboratory,DepartmentofFunctionalGenomics,DepartmentofBiology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2010年48期
• 关键词: HEPATITIS B VIRUS HEPATITIS B VIRUS X protein ALCOHOL Chronic liver disease Oxid
• 基金项目: Supported by The 21st Century Frontier Program in the Functional Human Genome Project, No. HGM0200934,the International Collaboration Program of Science and Technology, No. FGM0600914,the Ministry of

Long term hepatitis B virus (HBV) infection is a major risk factor in pathogenesis of chronic liver diseases,including hepatocellular carcinoma (HCC). The HBV encod-ed proteins,hepatitis B virus X protein and preS,appear to contribute importantly to the p