Scavenger receptor BI: A multi-purpose player in cholesterol and steroid metabolism

• 作 者: Menno Hoekstra Theo JC Van Ber
• 机 构: DivisionofBiopharmaceuticsLeiden/AmsterdamCenterforDrugResearchGorlaeusLaboratories
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2010年47期
• 基金项目: Supported by Top Institute Pharma (TIPharma Project T2-110, Hoekstra M and Van Berkel TJC),Grant 2008T070 from the Netherlands Heart Foundation (Hoekstra M),VIDI Grant 917.66.301 from the Netherlands

Scavenger receptor class B type Ⅰ (SR-BI) is an important member of the scavenger receptor family of integral membrane glycoproteins. This review highlights studies in SR-BI knockout mice, which concern the role of SR-BI in cholesterol and steroid metabol