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一、引言1817年Berzelius首次鉴定硒是一种化学元素。然而,过了140年,到1957年Schwarz等才认识到硒是生物的必需元素。1969年Thompson等证明硒除了可代替维生素E外,还有其独特的功能,从而进一步明确了硒的必需性。硒的生理作用由Rotruck等、Flohe等于1973年确立。他们发现硒是谷胱甘肽过氧化物酶(GSH-Px)结构中的必需成分。由此人们对硒在细胞抗氧化物防御机理中所起的作
I. Introduction Berzelius first identified 1817 as a chemical element in selenium. However, after 140 years, Schwarz et al. Realized in 1957 that selenium was an essential element of biology. In 1969, Thompson proved selenium in addition to vitamin E can be replaced, but also has its unique features, thereby further clarifying the necessity of selenium. The physiological role of selenium was established by Rotruck et al., Flohe et al. They found that selenium is an essential component of the glutathione peroxidase (GSH-Px) structure. As a result, people play a role in the defense mechanism of cellular antioxidants