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本文前瞻性的对32例星形细胞瘤患者做了动态CT扫描。结果显示:TBR_L值、HU_(L-F)值与星形细胞瘤的病理分级明显相关(P<0.01),代表肿瘤组织在5min末细胞外间隙剩余的碘,系血脑屏障破坏造成碘的回收障碍所致,肿瘤恶性程度越高,其对碘的廓清率越低。HU_P值及TBR_P值表示肿瘤的强化程度,与星形细胞瘤病理分级相关(P<0.05)。本文还给出了时间-密度曲线峰值后1min碘廓清率的计算公式,在本组病例中也显示有一定的差异性。本组指标对星形细胞瘤级别的判断总体敏感性为83.3%,特异性为86.7%,准确率为87.2%,与常规CT相比,动态CT扫描曲线参数分析可明显提高术前定性的特异性和准确性。
This article prospectively performed dynamic CT scans on 32 patients with astrocytomas. The results showed that the TBR_L and HU_(L-F) values were significantly associated with the pathological grade of astrocytoma (P<0.01), representing the remaining iodine in the extracellular space of the tumor tissue at the end of 5 min, which caused the destruction of the blood-brain barrier. Due to the recovery of iodine, the higher the malignancy of the tumor, the lower the clearance rate of iodine. The HU_P value and TBR_P value indicate the degree of tumor enhancement, which is related to the pathological grade of astrocytoma (P<0.05). This paper also gives the calculation formula of the iodine clearance rate after the peak of the time-density curve in 1 min. It also shows some differences in this group of patients. The overall sensitivity of this group of indicators for the determination of astrocytoma grade was 83.3%, the specificity was 86.7%, and the accuracy rate was 87.2%. Compared with conventional CT, dynamic CT scan curve parameters analysis can be significantly Improve pre-surgical qualitative specificity and accuracy.