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对61例急性髓性白血病(AML)在HOAP方案第一疗程化疗第6天骨髓象作前瞻性观察。发现此时限骨髓白血病原始细胞百分率<40%并骨髓白血病原始细胞降低指数>50的病例完全缓解(CR)率达80.6%(25/31例),以上指标一项或二项不符合者仅11.1%(3/27例)病例CR(P<0.001)。表明本法可较早地预测HOAP方案治疗AML的效果。
61 cases of acute myeloid leukemia (AML) were prospectively observed on the 6th day of the first course of chemotherapy with HOAP. The complete remission (CR) rate of 80.6% (25/31 cases) was found in cases with myeloproliferative myelomonocytic leukemia cells <40% and myeloid leukemia blast cell declining index >50. One or two of the above indicators were not met. Only 11.1% (3/27 cases) of cases had CR (P < 0.001). It shows that this method can predict the effect of HOAP treatment on AML earlier.