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本文采用HA方案治疗慢性粒细胞白血病(慢粒)加速期14例,取得了较好的疗效。表现为临床症状明显减轻或消失;血红蛋白及血小板明显上升(P<0.05);白细胞及骨髓原始粒细胞明显下降(P<0.01);脾脏明显缩小(P<0.01);患者生存期延长1—2年以上。作者认为HA方案是慢粒加速期的一种行之有效的治疗措施。
This article uses HA regimen in the treatment of chronic myelogenous leukemia (CML) in the accelerated phase in 14 cases and achieved good results. The clinical symptoms were significantly reduced or disappeared; hemoglobin and platelets were significantly increased (P<0.05); white blood cells and bone marrow blasts were significantly decreased (P<0.01); spleens were significantly reduced (P<0.01); survival time was extended 1-2 More than a year. The authors believe that the HA regimen is an effective therapeutic measure for the accelerated phase of chronic granulation.