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目的:对比观察角膜缘干细胞移植与羊膜移植治疗翼状胬肉的效果。方法:将325例翼状胬肉患者随机分为角膜缘干细胞移植组(A组)和羊膜移植组(B组)。其中A组215例(280眼),B组110例(145眼),术后观察随访6～12个月,统计创面愈合时间及复发情况。结果:A组中有9眼复发,复发率为3.21%;B组有12眼复发,复发率为8.28%。结论:角膜缘干细胞移植与羊膜移植对治疗翼状胬肉均有疗效,其中角膜缘干细胞移植复发率低,角膜创面修复快,效果更好。
Objective: To compare the effects of limbal stem cell transplantation and amniotic membrane transplantation for the treatment of pterygium. Methods: 325 patients with pterygium were randomly divided into limbal stem cell transplantation group (A group) and amniotic membrane transplantation group (B group). One group of 215 cases (280 eyes), B group of 110 cases (145 eyes), postoperative follow-up of 6 to 12 months, the statistics of wound healing time and recurrence. Results: In group A, 9 eyes relapsed and the recurrence rate was 3.21%. In group B, 12 eyes relapsed and the recurrence rate was 8.28%. CONCLUSION: Both limbal stem cell transplantation and amniotic membrane transplantation are effective in the treatment of pterygium. Including limbal stem cell transplantation, the recurrence rate is low, and the corneal wound repair is faster and the effect is better.