论文部分内容阅读
用抗生素治疗放线菌病的疗效取决于病原体对抗生素的敏感性,药物进入病灶的程度及其在血液、病灶中保持治疗浓度的时间等因素。据报道,链霉素、红霉素、氨苄青霉素、青霉素、林可霉素、甲氧西林和利托菌素中,只有利托菌素在体外实验中以61μg/ml浓度可抑制放线菌菌株生长,在体内实验中以125μg/ml浓度可达高治疗浓度,并维持24小时以上。由于利托菌素具有趋肺性,本文旨在通过动物实验方法研究利托菌素治疗肺放线菌病的疗效。实验动物为体重1800～2000g的家兔,实
The efficacy of antibiotic treatment of actinomycosis depends on the sensitivity of the pathogen to the antibiotic, the extent to which the drug has entered the lesion, and the time it takes to maintain the therapeutic concentration in the bloodstream, lesion, and the like. It has been reported that only streptomycin in streptomycin, erythromycin, ampicillin, penicillin, lincomycin, methicillin and litorin, inhibits actinomycetes at a concentration of 61 μg / ml in vitro Strain growth in vivo experiments with 125μg / ml concentration up to the high therapeutic concentration, and maintain more than 24 hours. Due to the tendency of Listerin to become pulmonary, the aim of this study was to investigate the efficacy of Lactamycin in the treatment of pulmonary actinomycetes by animal experiments. Experimental animals for the weight of 1800 ~ 2000g rabbits, real