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本文报道使用噻唑烷酸(硫杂脯氨酸)治疗慢性病毒性肝炎20例,其中包括慢性迁延型肝炎(CPH)15例、慢性活动性肝炎(CAH)5例。研究结果表明,噻唑烷酸对CPH的有效率为(86％)13/15;对CAH的有效率为(80％)4/5。从乙型肝炎病毒标志(HBVM)检测结果看,似乎有一定疗效。在服用过程中未见副作用。作者等认为噻唑烷酸治疗慢性病毒性肝炎,似有进一步扩大临床研究的必要,以提供治疗慢性病毒性肝炎较好的替代药物。
In this paper, 20 cases of chronic viral hepatitis were treated with thiazolidine (thioproline), including 15 cases of chronic persistent hepatitis (CPH) and 5 cases of chronic active hepatitis (CAH). The results showed that the effective rate of thiazolidine on CPH was (86%) 13/15; the effective rate of CAH was (80%) 4/5. From the hepatitis B virus (HBVM) test results, there seems to be a certain effect. In the course of taking no side effects. The authors believe that thiazolidine treatment of chronic viral hepatitis, seems to further expand the clinical research necessary to provide a better alternative treatment of chronic viral hepatitis.