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阿司匹林和噻氯匹定(ticlopidine),是两个有效的抗血小板药,能降低卒中复发危险。本文比较两药对女性卒中的预防效果。阿司匹林预防卒可试验 Grotta复习文献后指出,一过性脑缺血发作(TIA)后预防性口服阿司匹林,可使卒中发生率降低25~30%;最适剂量为每日325mg。这种小剂量几乎完全抑制环氧合酶,阻止血小板内生成血栓素A_2,从而抑制血小板聚集。并用其他抗血小板药如磺吡酮(硫氧唑酮)或双嘧
Aspirin and ticlopidine are two potent antiplatelet agents that reduce the risk of stroke recurrence. This article compares the preventive effects of the two drugs on stroke in women. Aspirin Preventive Stroke Test Grotta reviewed the literature and found that prophylactic oral aspirin after a transient ischemic attack (TIA) reduced the incidence of stroke by 25-30%; the optimal dose was 325 mg daily. This small dose almost completely inhibits cyclooxygenase, preventing the formation of thromboxane A 2 in platelets, thereby inhibiting platelet aggregation. And with other anti-platelet drugs such as sulfinpyrazone (thioxazolone) or dipyrimidine