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病例介绍 患儿 男,6岁。22个月前发热 双侧膝关节肿胀疼痛,右侧明显,予以地塞米松、洁霉素等治疗,5天后体温正常,关节疼痛缓解,肿胀未减轻。6个月前,双腕关节各有一约1cm×1cm的肿物,无热痛及活动受限,无进行性加重。4个月前再次发热,弛张型,伴双膝关节明显肿胀疼痛,进行性加重,不能活动。当地行“右膝滑膜切除术”,术后病理诊断“绒毛结节性滑膜炎,符合类风湿性关节炎”。遂予以阿司匹林、雷公藤多甙、强的松等治疗,无明显效果。近两个月间断发热,曾患“肺炎”,抗感染治疗好转。患儿系第三胎,1岁后常间隔半个月患1次“感冒”,
Case description Children male, 6 years old. 22 months ago, both sides of the knee joint fever pain, obvious right, dexamethasone, lincomycin and other treatment, 5 days after the normal body temperature, joint pain relief, swelling did not reduce. 6 months ago, the wrist each have about 1cm × 1cm of the tumor, no heat pain and limited mobility, no progressive increase. 4 months ago again fever, relaxation type, with obvious swelling and pain in both knees, progressive increase, can not activity. Local line “right knee synovectomy”, pathological diagnosis of “villonodular synovitis, in line with rheumatoid arthritis.” Then to aspirin, Tripterygium glycosides, prednisone and other treatment, no significant effect. Nearly two months off fever, had “pneumonia”, anti-infective treatment improved. Children with a third child, 1 year after the regular interval of two weeks suffering from a “cold”