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通常治疗沙眼的眼药水中,有採用磺胺乙酰鈉的溶液的,其濃度有10%,20%,30%等,个別医院也有採用15%的。溶液微鹼性,pH为7.2—7.4。在1955年下半年,上海有几个医疗單位使用磺胺乙酰鈉眼药水时,發現有变色的現象,初为淡綠,漸变深綠,然后变紫,再变藍,影响了药品的質量。但值得注意的是放在医院里的这种眼药水就不变色,發給病人使用一兩天后即發生变色現象了。我們將退回来的眼药水,进行了系統分析,除主要原料外,测出尚含有銘离子較多。我們推测銘离子的来源可能是原料在生产过程中接触金属銘的关
Usually treat trachoma eye drops, the use of sulfa sodium solution, the concentration of 10%, 20%, 30%, etc., also used 15% of individual hospitals. The solution is slightly alkaline with a pH of 7.2-7.4. In the second half of 1955, several medical institutions in Shanghai used sulfa sodium eye drops and found that there was a discoloration phenomenon. At first they were light green, gradually dark green, then purple and then blue, which affected the quality of medicines. But it is noteworthy that this eye drops placed in the hospital will not change color, sent to the patient to use after a day or two discoloration occurred. We will return the eye drops, a systematic analysis, in addition to the main raw materials, the measured ions are still more Ming. We speculate that the origin of ions may be the raw material in the production process of contact with the metal Ming Guan