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兴奋性氨基酸（ＥＡＡｓ）作为中枢神经系统兴奋性神经递质，当细胞外水平过高时具有神经毒性作用。研究表明，ＥＡＡｓ与帕金森氏病（ＰＤ）发病机理有关；ＥＡＡｓ拮抗剂有抗ＰＤ症状及多巴胺能神经元保护作用。
Excitatory amino acids (EAAs), the excitatory neurotransmitter of the central nervous system, have neurotoxic effects when extracellular levels are too high. Studies have shown that EAAs and Parkinson’s disease (PD) pathogenesis; EAAs antagonists have anti-PD symptoms and dopaminergic neuron protective effect.