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目的了解广州市某区2008年度流感发病及抗原变异情况,为制定流感防治策略提供科学依据。方法利用流感监测点定期采集的流感样标本,以MDCK细胞分离病毒,并应用红细胞凝集抑制法进行型别鉴定,对流感的病原学以及流感疫情监测情况进行统计分析。结果全年共监测咽拭子763份,分离病毒株80株,其中A(H1N1)型37株,A(H3N2)14株,B(Victoria)23株,B(Yamagata)6株。15岁以下人群发病最多,占流感样病例的65.00%。全年发生流感疫情2起,春季以B(Victoria)为主,夏季以A(H1N1)为主。结论全年广州市某区流感发病呈散发,并以H1N1亚型为主,15岁以下人群为流感高危人群,流感发病高峰出现在3月份和7月份。
Objective To understand the epidemic situation and antigenic variation of influenza in a certain area of Guangzhou in 2008 and provide a scientific basis for the development of influenza prevention and control strategies. Methods Influenza samples were collected periodically from influenza surveillance sites. The virus was isolated from MDCK cells and the type of erythrocyte agglutination inhibition was used to identify the type of influenza. The etiology of influenza and the monitoring of influenza epidemic were statistically analyzed. Results A total of 763 pharyngeal swabs were isolated and 80 strains were isolated. Among them, 37 were A (H1N1), 14 were A (H3N2), 23 were B (Victoria) and 6 were B (Yamagata). People under the age of 15 the most incidence, accounting for 65.00% of flu-like cases. There were 2 flu outbreaks throughout the year, with B (Victoria) in spring and A (H1N1) in summer. Conclusion The prevalence of influenza was distributed in a certain area of Guangzhou in the whole year. H1N1 subtype was the main cause. The crowd under 15 years old was at high risk of influenza. The peak incidence of influenza appeared in March and July.