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作者对四种不同肝病患者测定了血清GPDA,并以86例正常人作为对照,结果表明原发性肝癌组、急性肝炎组、AFP低浓度阳性组与正常对照组相比较均有显著差异(P<0.01),肝血管瘤组与正常对照组间无显著差异:结果表明血清GPDA测定有助于肝癌与肝血管瘤间的鉴别诊断。GPDA与AFP无相关性,AFP阴性肝癌患者的GPDA阳性率达68.9%。此文对GPDA作为肝癌标记物的诊断价值作了有益的讨论
The authors measured serum GPDA in four different liver diseases and 86 normal people as controls. The results showed that there were significant differences between the primary liver cancer group, acute hepatitis group, AFP low concentration positive group and the normal control group (P <0.01) There was no significant difference between the hepatic hemangioma group and the normal control group. The results showed that the serum GPDA assay was helpful for the differential diagnosis between hepatocellular carcinoma and hepatic hemangioma. There was no correlation between GPDA and AFP. The positive rate of GPDA in patients with AFP-negative liver cancer was 68.9%. This article makes a useful discussion on the diagnostic value of GPDA as a marker for liver cancer.