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基体辅助激光解吸电离质谱是近几年才发展起来的一种新技术，它在生命科学研究中具有广阔的应用前景．对基体辅助激光解吸电离质谱技术的基本原理，运用基体辅助激光解吸电离质谱法研究蛋白质分子量的测定，蛋白质混合物的分离鉴定以及用基体辅助激光解吸电离质谱技术进行超快速的蛋白质序列分析和ＤＮＡ序列分析的可行性和存在的问题作了介绍和讨论．
Matrix assisted laser desorption ionization mass spectrometry is a new technology developed in recent years, which has broad application prospects in life science research. The basic principle of matrix-assisted laser desorption ionization mass spectrometry (MS / MS) was studied. The matrix-assisted laser desorption ionization mass spectrometry was used to study the determination of protein molecular weight, the separation and identification of protein mixtures and the ultrafast protein sequence analysis and DNA sequencing by matrix assisted laser desorption ionization mass spectrometry The feasibility of the analysis and the existing problems were introduced and discussed.