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器官移植作为一种治疗某些器官失能性疾病的方法运用于临床以来,仅肾脏移植一项,世界上就有60000例以上。有关移植的各方面工作都得到了很大的发展,但由于异体排斥问题尚未得到很好解决,临床的移植工作目前处于停滞状态,等待着移植免疫的研究进展。本人设想了一种诱导特异性免疫耐受的方法,现叙述如下: 用除去了成熟免疫细胞的受者骨髓与供者的胸腺上皮性网状细胞共同培养,由于培养基中有供者的上皮性网状细胞,可
Since organ transplantation has been used clinically as a method of treating some organ-impaired diseases, there are more than 60,000 cases of kidney transplants in the world. All aspects of transplant work have been greatly developed, but because of the problem of allograft rejection has not been well resolved, the clinical transplant work is currently at a standstill, awaiting the progress of transplantation immunization research. I have envisaged a method of inducing specific immune tolerance, which is described as follows: co-culture of the donor’s thymus reticular cells with the recipient’s bone marrow from which the mature immune cells have been removed, since the donor’s epithelium Reticular cells can be