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目的:探索丙型肝炎病毒在口腔扁平苔藓发病中的意义。方法:应用PCR技术对60例口腔扁平苔藓患者进行了丙型肝炎病毒RNA的检测。结果:在60例口腔扁平苔藓患者中,其中7例丙型肝炎病毒RNA阳性,与对照组相比具有显著性差异(P<0.05);且丙型肝炎病毒RNA阳性患者的损害均表现为白纹伴糜烂。结论:在口腔扁平苔藓中,尤其是在糜烂伴白纹的口腔扁平苔鲜患者中,应用敏感的PCR技术检测血液中的丙型肝炎病毒RNA,不仅对于防治慢性肝炎,而且对于探索口腔扁平苔藓的病因与治疗均具有重要意义。
Objective: To explore the significance of hepatitis C virus in the pathogenesis of oral lichen planus. Methods: HCV RNA was detected in 60 patients with oral lichen planus by PCR technique. Results: Of the 60 patients with oral lichen planus, 7 of them were positive for hepatitis C virus RNA, which was significantly different from that of the control group (P <0.05). The lesions of hepatitis C virus RNA positive patients White with erosion. Conclusion: Detection of Hepatitis C virus RNA in blood by oral sensitive lichen planus in oral lichen planus, especially in patients with erosion and white-striped oral lichen planus, not only for the prevention and treatment of chronic hepatitis, but also for the exploration of oral lichen planus The etiology and treatment are of great significance.