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目的探讨双侧乳腺癌6例的临床特点及预后。方法回顾性分析双侧乳腺癌6例患者的临床资料,分析其病理特征和生存结果。结果本组6例双侧乳腺癌占我院同期乳腺癌患者的0.96%,均为女性患者。6例患者病理分期以0、Ⅰ、Ⅱ期为主,双侧病灶中雌激素受体、孕激素受体和人表皮生长因子受体2表达的一致性较高,分子分型以基底样型较多。死于内脏转移1例,从第二侧癌手术时间开始计算,生存时间为11个月;复发可能1例,另3例患者未见复发和转移。结论双侧乳腺癌的病灶可表现出更相似的分子生物学特征,患者的预后与双侧病灶中分期较重的一侧相关。
Objective To investigate the clinical features and prognosis of 6 cases of bilateral breast cancer. Methods The clinical data of 6 patients with bilateral breast cancer were retrospectively analyzed. The pathological features and survival results were analyzed. Results The group of 6 cases of bilateral breast cancer accounted for 0.96% of patients with breast cancer in our hospital over the same period, all female patients. The pathological staging of 6 patients was mainly in stage 0, Ⅰ and Ⅱ. The consistency of the expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 in bilateral lesions was high. The molecular typing was basal-like More. 1 died of visceral metastases, from the second side of the cancer surgery time to start, the survival time was 11 months; 1 case of recurrence, and the other 3 patients did not relapse and metastasis. Conclusion Bilateral breast cancer lesions may show more similar molecular biological characteristics, the prognosis of patients with bilateral lesions in the staging of heavier side.