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研究了环丙基硼酸与芳基ω-卤代氧杂全氟烷基磺酸酯的交叉偶联反应, 发现在合适条件下, 经过渡金属催化, 立体专一的环丙基硼酸能与芳香类ω-卤代氧杂全氟烷基磺酸酯顺利偶联, 得到较高产率的交叉偶联产物. 对于含不同取代基的芳香类全氟磺酸酯, 使用不同类型的碱是重要的. 在该偶联过程中, 环丙基的构型保持不变, 从而提供了一种以酚类化合物和工业上价廉易得的ω-氯代氧杂全氟烷基磺酰氟为原料制备立体专一环丙烷衍生物的新途径.
The cross-coupling reaction of cyclopropylboronic acid with aryl ω-halooxafluoro perfluoroalkylsulfonates was studied. It was found that, under the appropriate conditions, the transition metal-catalyzed stereospecific cyclopropylboronic acid can react with aromatic The successful coupling of the class of ω-halooxaperfluoroalkylsulfonates gives higher yields of cross-coupled products.It is important to use different types of bases for aromatic perfluorosulfonates with different substituents In the coupling process, the cyclopropyl configuration remains unchanged, thereby providing a phenolic compound and the industrially readily available omega-chlorooxafluoroalkylsulfonyl fluoride as raw material New Approach to Prepare Stereo - Specific Cyclopropane Derivatives.