论文部分内容阅读
用放射免疫法对４３例女性绝经期后视网膜色素变性（ＲＰ）患者行血清性激素测定。结果：ＲＰ组与其它眼病组和正常组比，雌二醇（Ｅ２）、睾酮（Ｔ）及Ｅ２／Ｔ降低，催乳素（ＰＲＬ）、促卵泡成熟激素（ＦＳＨ）、促黄体生成激素（ＬＨ）、孕酮（Ｐ）升高。与正常组相比除ＬＨ外，其余指标差异均有非常显著意义（Ｐ＜０．０１）；与其它眼病组比较，除Ｅ２／Ｔ外，其余指标均有显著或非常显著的差异（Ｐ＜０．０５，Ｐ＜０．０１）。此外，ＲＰ患者的病情轻重之间各指标亦有差异。结果提示，性激素内环境的紊乱、失调与ＲＰ发病有关。
Serum sex hormone levels were measured in 43 women with postmenopausal retinitis pigmentosa (RP) by radioimmunoassay. Results: Compared with other ophthalmopathy group and normal group, the levels of E2, T and E2 / T were lower in RP group than those in normal eye group (P <0.05). The levels of prolactin (PRL), follicle stimulating hormone (FSH), luteinizing hormone ), Progesterone (P) increased. Compared with the other two groups, there were significant differences between the two groups except for LH (P <0.01). Compared with other groups, all indexes except E2 / T had significant or very significant difference (P < 0.05, P <0.01). In addition, RP patients with different severity indicators vary. The results suggest that sex hormones within the environment disorders, disorders and the pathogenesis of RP.