论文部分内容阅读
目前,全球约有17亿,近1/3人口感染结核,作为单一传染病已成为最大的死亡原因。肺结核为其最主要的表现形式及传染源,居高不下的发病率及死亡率,除因不能得到及时正规的抗痨治疗外,其次就是由于社会的、生物的、理化的环境因素及自身遗传因素综合作用而出现兼症这系列关联性疾病所致,使表现复杂化、病情严重化、久治不愈或导致死亡。 1 糖尿病糖尿病漫长的发展过程中,其病理生理主要表现为代谢紊乱所致的高血糖、高脂蛋白、高血脂、低蛋白血症(白蛋白及IeG降低)、负氮平衡及细胞免疫和体液免疫功能下降,这些因素均可使内源性隐性感染变为活动性,或感染外源性结核。实验证明,结核菌在血糖增加和有酮体牛成的条件下易于繁殖,高血脂、高脂蛋白血症
At present, about 1.7 billion people and about 1/3 of the world’s population are infected with tuberculosis. As a single contagious disease, it has become the biggest cause of death. Tuberculosis is the most important manifestation and source of infection. The morbidity and mortality rates are still high. Second, due to the lack of timely anti-tuberculosis treatment, the second is due to social, biological, physical and chemical environmental factors and their own genetic The combined effect of factors and the occurrence of this series of related diseases caused by complications, the performance of complex, serious condition, prolonged treatment or cause death. A long process of diabetes mellitus development, the pathophysiology mainly due to metabolic disorders caused by hyperglycemia, hyperlipoproteinemia, hyperlipidemia, hypoproteinemia (albumin and IeG decreased), negative nitrogen balance and cellular immunity and body fluids Immune function decline, these factors can make endogenous latent infection become active, or infected with exogenous TB. Experiments show that tuberculosis bacteria in the blood glucose and ketoconazole conditions easy to reproduce, hyperlipidemia, hyperlipoproteinemia