论文部分内容阅读
近年来,随着慢性非传染性疾病的发病率升高,人们的健康意识越来越强,花色苷因其具有的保健效应而备受青睐。花色苷是一种植物化学物,是多酚的主要组成成分,主要存在于深色的水果、蔬菜、谷物中,人类可以通过饮食摄取大量的花色苷。花色苷具有抗氧化、抗衰老、抗炎、抗癌的生理功能,花色苷还能减少血小板聚集、保护血管,从而对心血管疾病发挥其预防保健功能。近些年研究发现花色苷对酒精性肝病也有防治作用。酒精性肝病(ALD)是由于长期大量的摄入酒精而导致肝脏损伤。由初期的酒精性脂肪肝,进一步演变为酒精性肝炎、酒精性肝纤维化、酒精性肝硬化,甚至可以发展为酒精性肝癌。本文将对花色苷在酒精性肝病的发生发展中的作用及机制进行简明综述。
In recent years, as the incidence of chronic non-communicable diseases increases, people’s awareness of health is getting stronger and stronger. Anthocyanins are favored for their health effects. Anthocyanins are a kind of phytochemical, which is the main component of polyphenols. They are mainly found in dark fruits, vegetables and cereals. Human beings can consume a large amount of anthocyanins through their diet. Anthocyanins with antioxidant, anti-aging, anti-inflammatory, anti-cancer physiological functions, anthocyanins can reduce platelet aggregation, protect blood vessels, which play a preventive role in cardiovascular disease health care function. In recent years, studies have found that anthocyanins also have prevention and treatment of alcoholic liver disease. Alcoholic liver disease (ALD) is the result of liver damage caused by the prolonged intake of alcohol. From the initial alcoholic fatty liver, further evolution of alcoholic hepatitis, alcoholic liver fibrosis, alcoholic cirrhosis, and even can develop into alcoholic liver cancer. This article will give a brief overview of the role and mechanism of anthocyanins in the occurrence and development of alcoholic liver disease.