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冠心病是严重危害人民健康的一种多发病常见病。采用中西医结合利用中医活血化瘀防治冠心病心绞痛近年来已广泛应用于临床。我院冠心病研究室于1974年6月开始以冠宁注射液治疗冠心病心绞痛,获得了较好的效果。经我校生理教研组、血凝研究组进行了研究,发现冠宁注射液(以下简称本品)对离体兔心有增加冠脉流量、抗血液凝固及促进纤维蛋白溶解系统的作用。丹参为唇形科鼠尾草属植物丹参Salvia mil-tiorrhiza Bunge以根入药。据李时珍;丹参活血,通心包络。根含结晶性呋喃并菲醌类色素、鼠尾草酚和维生素E。丹参对脑下垂体后叶素引起心肌缺血,有扩张冠状动脉增加血流量的作用。川芎为伞形科藁本属植物川芎Ligusticum wallichiiFranch.以干燥根状茎入药。据《本草纲目》转引《孙氏集效方》,丹参治“一切心
Coronary heart disease is a common disease that seriously endangers people’s health. The use of traditional Chinese medicine and Western medicine in the use of traditional Chinese medicine for blood circulation to prevent and treat coronary heart disease angina has been widely used in clinical recent years. In June 1974, Coronary Heart Disease Research Laboratory in our hospital began treating coronary heart disease and angina pectoris with Guan Ning injection, and achieved good results. After studying in our school’s physiology and teaching group and blood coagulation research group, we found that Guanning injection (hereinafter referred to as this product) has the effect of increasing coronary blood flow, anti-blood coagulation, and promoting fibrinolysis system in isolated rabbit hearts. Salvia miltiorrhiza Salvia mil-tiorrhiza Bunge is used as root medicine. According to Li Shizhen; Salvia blood circulation, through heart enveloping. The root contains crystalline furanophenanthrene dyes, carnosol and vitamin E. Salvia miltiorrhiza can cause myocardial ischemia in the pituitary pituitrin, which has the effect of expanding the coronary artery to increase blood flow. Chuanxiong is an umbrella plant of the genus Ligusticum wallichiiFranch. It is used as a dry rhizome. According to the “Compendium of Materia Medica,” referring to “Sun’s Collection of Effectiveness”, Dan Sangzhi "all hearts