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本文旨在评价用多聚酶链反应(PCR)法早期诊断结核性脑膜炎(TBM)的价值,并与常规细菌学及酶联免疫吸附测定(ELISA)法比较。病人和方法参加研究的85例患者,34例为怀疑 TBM 组,51例为非 TBM 对照组。TBM主要诊断标准:发热、头痛、颈强直2周以上。辅助诊断标准:脑脊液化验,CT 扫描表现;中枢神经系统以外结核证据;临床抗结核治疗有效。TBM 组分为极可能组:主要标准加3项辅助标
This article aims to evaluate the value of early detection of tuberculous meningitis (TBM) by polymerase chain reaction (PCR) and to compare it with routine bacteriological and enzyme-linked immunosorbent assay (ELISA). Eighty-five patients and patients enrolled in the study, 34 with suspected TBM and 51 with non-TBM. TBM main diagnostic criteria: fever, headache, neck stiffness for more than 2 weeks. Auxiliary diagnostic criteria: cerebrospinal fluid tests, CT scans; evidence of tuberculosis outside the central nervous system; clinical anti-TB treatment is effective. TBM component is the most likely group: the main standard plus three auxiliary standard