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一九八九年确定甲、乙、丙、丁、戊型肝炎病毒后,各国学者在研究中相继提出了其他肝炎病毒如 HFV、HGV 等存在的可能性。1995年,Genelab 技术公司的 JM.Linnen 等又克隆并分析了两个新的病毒基因序列,命名为庚型肝炎病毒(HGV),极大地激发了学者们的研究热情.日本 M Mukaide 等研究了来自16个国家的146个 HGV5’端非编码区序列后,认为庚型肝炎病毒存在三个不同的种系群.第一群以 GBV-C 为代表;第三群以 HGV 为代表,另外存在第二群,主要流行于亚洲地区.GBV-C 较 HGV 进化早,HGV 是最新进化的一群,主要流行于亚欧美.
After the A, B, C, D and E hepatitis viruses were identified in 1989, scholars in various countries successively raised the possibility of existence of other hepatitis viruses such as HFV and HGV. In 1995, JMLinnen et al. Of Genelab Technologies also cloned and analyzed two new viral gene sequences, named Hepatitis G Virus (HGV), which greatly stimulated the scholars’ research enthusiasm.Mukaide et al After 146 HGV 5 ’non-coding region sequences from 16 countries, it is considered that there are three different germline groups of hepatitis G virus, the first group is represented by GBV-C, the third group is represented by HGV, and the other exists The second group, mainly popular in Asia, GBV-C evolved earlier than HGV, HGV is the latest evolution of a group, mainly popular in Asia, Europe and the United States.