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我们于1964年秋收治钩端螺旋体引致Guillain—Barre综合征者3例,现报告如下: 讨论本文病例皆为农业社员,在洪水期间有与疫水接触之历史。有典型钩端螺旋体病的临床症状,补体结合试验阳性,血中培养出钩端螺旋体,经凝溶试验证实为“396”型,故钩端螺旋体病的诊断已确立。此外,病人在急性期热降时,相继出现对称弛缓性瘫痪,肌张力低下,腱反射消失,四肢远端感觉障碍,脑脊液呈蛋白—细胞分离现象,这符合Guillain—Barre综合征的临床表现。
In the autumn of 1964, we treated 3 cases of Leptospira caused Guillain-Barre syndrome. The report is as follows: All the cases discussed in this paper are agricultural members, and have a history of contact with the infected water during the flood season. Clinical symptoms of typical leptospirosis, complement fixation test was positive, the blood culture of Leptospira, confirmed by the coagulation test for the “396” type, so the diagnosis of leptospirosis has been established. In addition, patients with symmetrical flaccid paralysis, low muscle tension, disappearance of tendon reflexes, distal sensory disturbances, and protein-cell dissociation of the cerebrospinal fluid were observed in the acute phase of fever. This is consistent with the clinical manifestations of Guillain-Barre syndrome.