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目的：观察头孢羟氯苄三联疗法根除幽门螺杆菌（Hp）的临床应用价值。方法：对30例Hp阳性的十二指肠球都溃疡病人用头孢羟氨苄、奥美拉唑、甲硝唑三联疗法治疗2周并与25例行阿莫西林、奥美拉唑、甲硝唑三联疗法的病人进行对照。结果：治疗组与对照组停药4周后Hp根除率分别为83％（25／30）及84％（21／25）（P＞0．05），溃疡愈合率分别为：90／（27／30）及92％（23／25）（P＞0．05）。治疗组不良反应少。Hp对头孢羟氨苄的敏感率达90％。结论：以头孢羟氨苄为中心的三联疗法能有效的根除Hp，不良反应少，值得进一步尝试。
Objective: To observe the clinical value of cefotynil triad therapy in eradicating Helicobacter pylori (Hp). Methods: Thirty cases of Hp-positive duodenal ulcer patients were treated with cefadroxil, omeprazole and metronidazole triple therapy for 2 weeks and 25 patients with amoxicillin, omeprazole, Patients with azole triple therapy were controlled. Results: The Hp eradication rates in treatment group and control group were 83% (25/30) and 84% (21/25) respectively after 4 weeks’ withdrawal (P> 0.05), and the healing rates of ulcer were 90 / (27 / 30) and 92% (23/25) (P> 0.05). The treatment group had fewer adverse reactions. Hp on cefadroxil sensitive rate of 90%. CONCLUSION: Triple therapy with cefadroxil as the center can effectively eradicate Hp and has few side effects. It is worth further attempts.