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目的:分析我院不良反应发生的特点,为临床合理用药提供参考。方法:收集我院2010～2011年上报的158例不良反应报告,对ADR病例中患者年龄、性别,涉及药品种类、临床表现及累及器官,以及ADR转归、预后等信息进行统计分析。结果:158例ADR报告中以女性及老年患者居多,给药途径以静脉滴注较多,所涉及药品以抗感染药和中成药发生例次较高,临床表现以皮肤过敏及附件损害为主,严重病例10例,无死亡病例。结论:应重视分析ADR报告资料,特别是抗感染药及中药注射剂的临床合理应用,及时将信息反馈给临床,以促进临床合理用药。
Objective: To analyze the characteristics of adverse reactions in our hospital and provide references for clinical rational drug use. Methods: A total of 158 ADRs reported in our hospital from 2010 to 2011 were collected to analyze the age, gender, type of drug, clinical manifestations and organs involved in ADR, as well as the prognosis and prognosis of ADR. Results: Of the 158 ADR cases, most of them were female and elderly patients, intravenous drip was administered more frequently, and the cases involving anti-infectives and proprietary Chinese medicines were higher in clinical samples. The main clinical manifestations were skin allergy and accessory damage , 10 cases of serious cases, no deaths. Conclusion: It is necessary to pay attention to the analysis of ADR report data, especially the clinical application of anti-infectives and traditional Chinese medicine injections. The information should be fed back to the clinic in time to promote clinical rational use of drugs.