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磷脂酶C（PLC）能将细胞膜上的二磷酰磷脂酰肌醇（PIP2）水解成第二信使二酰甘油及三磷酰肌醇，在细胞间信号传导及细胞增殖方面起重要作用。PLC抑制剂有望成为细胞生长抑制剂及研究细胞间信号传导机理的有效试剂。作者通过测定IC50，比较研究了从苦参Sophoraflavesens根中分得
Phospholipase C (PLC) can hydrolyze diphosphophosphatidyl inositol (PIP2) on the cell membrane into second messenger diacylglycerol and triphosphoryl inositol, which plays an important role in cell-cell signaling and cell proliferation. PLC inhibitors are expected to be effective inhibitors of cell growth and to study the mechanism of signal transduction between cells. The authors comparatively studied the distribution of Sophoraflavesens roots by measuring IC50.