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目的探讨和研究不同给药途径对于人工流产术的手术效果的影响。方法选取胜利石油管理局妇幼保健院近年来收治的144例行人工流产术终止妊娠的患者的临床资料作为研究对象,按照随机分组的原则将之分为观察组和对照组,每组各72例,其中对照组进行舌下含服给药;观察组进行阴道后穹窿给药,记录和对比两组患者各项手术指标及术后不良反应发生率。结果两组患者在手术时间、术中出血量对比差异无统计学意义(P>0.05),观察组的宫口有效扩张率略低于对照组,差异无统计学意义(P>0.05);但观察组的术后不良反应发生率上明显优于对照组,差异具有统计学意义(P<0.05)。结论不同的给药途径对于人工流产术的效果影响有明显不同,阴道后穹窿放置米索前列醇能够明显提高宫口扩张有效率及减少不良反应的发生率,值得在临床上加以推广和应用。
Objective To investigate and study the effect of different route of administration on the surgical effect of induced abortion. Methods The clinical data of 144 cases of termination of pregnancy induced abortion by Shengli Petroleum Administration Maternal and Child Health Hospital in recent years were selected as research objects and divided into observation group and control group according to the principle of randomization, , In which the control group sublingual administration; observation group vaginal fornix administration, recording and comparing the two groups of patients with various surgical indicators and the incidence of postoperative adverse reactions. Results There was no significant difference in operative time and intraoperative blood loss between the two groups (P> 0.05). The effective expansion rate of cervix in the observation group was slightly lower than that of the control group (P> 0.05). However, there was no significant difference between the two groups The incidence of postoperative adverse reactions in the observation group was significantly better than that in the control group, the difference was statistically significant (P <0.05). Conclusions Different routes of administration have significant effects on the effect of induced abortion. The placement of misoprostol in vaginal posterior fornix can obviously improve the efficiency of cervical dilatation and reduce the incidence of adverse reactions, so it is worth to be popularized and applied clinically.