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无论是三足鼎立也好,还是八分天下也好,糖尿病发病的核心因素,依然是胰岛素β细胞的伤害,或者说2型糖尿病发病机制的关键因素是β细胞功能失调。1正常的胰岛β细胞悉知胰岛素是体内唯一的降糖激素,通过胰岛素调节着细胞正常生长发育的能量物质代谢。正常机体胰岛素β细胞是胰岛素唯一的生成场所,是组成胰岛的主要成员,正常人体约有17～200万个胰岛,约占胰腺总体积的1%左右,人胰岛主要有α、β、D、PP、D_1等五种类型细胞,β细胞占胰岛细胞的75%,其分泌大小不等(直径225～375nm)的含胰岛素的颗粒。正常人在血糖的调控
Whether it is the three pillars Ye Hao, or eight points world Ye Hao, the core factor in the pathogenesis of diabetes, is still the injury of insulin beta cells, or type 2 diabetes, the key factor is the pathogenesis of β-cell dysfunction. 1 normal pancreatic islet beta cells know that insulin is the only hypoglycemic hormone in the body, through the regulation of insulin cells normal growth and development of energy metabolism. Normal body insulin β cells are the only place where insulin is formed, and are the main members of the islet. The normal human body is about 17 to 2 million islets, accounting for about 1% of the total pancreas. The human islets mainly include α, β, D, PP, D_1 and other five types of cells, β cells accounting for 75% of islet cells, which secrete insulin-containing particles of varying sizes (diameter 225 ~ 375nm). Normal blood glucose in the regulation