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鉴于T细胞和MHC在疟疾免疫中所起的重要作用,有效的恶性疟原虫T细胞疫苗的设计,应将已确定的T细胞决定簇进行组合,使其能与多价MHC基因产物结合,并能对抗体的产生以及抗体非依赖性细胞免疫起
Given the important role that T cells and MHC play in malaria immunity, the design of an effective Plasmodium falciparum T cell vaccine should allow the combination of established T cell determinants to allow binding to multivalent MHC gene products and Can produce antibodies and antibody-independent cellular immunity